These modifications are minor and will be discussed.ĭigital tandem mass filter digital waveform technology higher stability zones spreadsheet stability diagrams theoretical comparison of sine and digital tandem mass filters. Our method of generating waveforms can meet this demand however, modifications to our current printed circuit board must be made. The creation of these mass window offsets requires waveform generation that can obtain high duty cycle resolution. For the tandem digital mode to be successful, the duty cycles of each quadrupole must be precisely controlled because the duty cycle differences required to shift the mass windows are small. A first precursor mass window and the corresponding first product ion spectrum are selected from a plurality of overlapping stepped precursor mass windows. This makes the digital tandem mass filter feasible as a commercial product. However, unlike sine mass filters, the mass range of a digital system is not limited. The work presented here shows that a fixed AC voltage digital tandem mass filter can only operate in higher stability zones. When the frequency, phase, and voltage of each quadrupole are identical, there theoretically are no changes to the Mathieu parameters to cause ion excitation and loss during transition between the quadrupole pair. Both quadrupoles operate at the same frequency, phase, and voltage. The tandem mass window is created when the individual filters are operated with two slightly different duty cycles. Digital tandem mass filters depart from convention because they do not change voltage.
MMASS WINDOWS CODE
The code was last tested against the following versions of said libraries and it is known to not work properly with current versions. Same is true for all the dependencies such as wxPython and NumPy. Sine wave systems create this offset through voltage changes. Requirements The mMass code was developed under Python 2 and has never been updated to Python 3. The tandem filter resolution and transmission are adjusted by changing the amount of offset separating the mass windows of the individual filters. The improvement in transmission is owed to the larger acceptance of the low-resolution quadrupoles. Lower your energy costs and improve your comfort with rebates from Mass Save. Tandem operation provides improved resolution and transmission compared to a single mass filter operated with the same mass window. In principle, the overlap of the two individual mass windows defines the tandem window.
MMASS WINDOWS SERIES
A tandem mass filter consists of two low-resolution mass filters arranged in series that operate with a small offset between their mass windows.
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